5V93
Cryo-EM structure of the 70S ribosome from Mycobacterium tuberculosis bound with Capreomycin
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (0) | 50S ribosomal protein L32 | polymer | 57 | 6525.8 | 1 | UniProt (A0A045IMI5) Pfam (PF01783) UniProt (by SIFTS) (P9WH99) | Mycobacterium tuberculosis | |
| 2 | B (1) | 50S ribosomal protein L33 | polymer | 55 | 6512.6 | 1 | UniProt (A0A045HU86) | Mycobacterium tuberculosis | |
| 3 | C (2) | 50S ribosomal protein L34 | polymer | 47 | 5611.6 | 1 | UniProt (A0A1L6JUG3) Pfam (PF00468) UniProt (by SIFTS) (P9WH93) | Mycobacterium tuberculosis | |
| 4 | D (3) | 50S ribosomal protein L35 | polymer | 64 | 7241.4 | 1 | UniProt (A0A045KKY9) Pfam (PF01632) UniProt (by SIFTS) (P9WH91) | Mycobacterium tuberculosis | |
| 5 | E (4) | 50S ribosomal protein L36 | polymer | 37 | 4323.2 | 1 | UniProt (A0A1L6JSF4) Pfam (PF00444) UniProt (by SIFTS) (P9WH89) | Mycobacterium tuberculosis | |
| 6 | F (6) | 50S ribosomal protein L31 | polymer | 80 | 8770.1 | 1 | UniProt (A0A045HLX7) Pfam (PF01197) UniProt (by SIFTS) (P9WHA1) | Mycobacterium tuberculosis | |
| 7 | G (A) | 23S rRNA | polymer | 3138 | 1017792.6 | 1 | GenBank (984989958) | Mycobacterium tuberculosis | |
| 8 | H (B) | 5S rRNA | polymer | 115 | 37097.2 | 1 | GenBank (1092945381) | Mycobacterium tuberculosis | |
| 9 | I (C) | 50S ribosomal protein L2 | polymer | 280 | 30644.0 | 1 | UniProt (A0A045H5T7) Pfam (PF01783) UniProt (by SIFTS) (P9WH99) | Mycobacterium tuberculosis | |
| 10 | J (D) | 50S ribosomal protein L3 | polymer | 217 | 23127.5 | 1 | UniProt (A0A045HU18) Pfam (PF00297) UniProt (by SIFTS) (P9WH87) | Mycobacterium tuberculosis | |
| 11 | K (E) | 50S ribosomal protein L4 | polymer | 223 | 23779.9 | 1 | UniProt (A0A045J9H1) Pfam (PF00573) UniProt (by SIFTS) (P9WH85) | Mycobacterium tuberculosis | |
| 12 | L (F) | 50S ribosomal protein L5 | polymer | 187 | 21052.3 | 1 | UniProt (A0A045HUU0) Pfam (PF00673) Pfam (PF00281) UniProt (by SIFTS) (P9WH83) | Mycobacterium tuberculosis | |
| 13 | M (G) | 50S ribosomal protein L6 | polymer | 179 | 19408.4 | 1 | UniProt (A0A045JJU1) Pfam (PF00347) UniProt (by SIFTS) (P9WH81) | Mycobacterium tuberculosis | |
| 14 | N (H) | 50S ribosomal protein L9 | polymer | 152 | 16196.7 | 1 | UniProt (A0A045JW48) Pfam (PF01281) Pfam (PF03948) UniProt (by SIFTS) (P9WH79) | Mycobacterium tuberculosis | |
| 15 | O (J) | 50S ribosomal protein L13 | polymer | 147 | 16333.9 | 1 | UniProt (A0A0T9D5H2) Pfam (PF00572) UniProt (by SIFTS) (P9WHE1) | Mycobacterium tuberculosis | |
| 16 | P (K) | 50S ribosomal protein L14 | polymer | 122 | 13419.6 | 1 | UniProt (A0A0U0S3A8) Pfam (PF00238) UniProt (by SIFTS) (P9WHD9) | Mycobacterium tuberculosis | |
| 17 | Q (L) | 50S ribosomal protein L15 | polymer | 146 | 15534.1 | 1 | UniProt (A0A0T7M0A0) Pfam (PF00828) UniProt (by SIFTS) (P9WHD7) | Mycobacterium tuberculosis | |
| 18 | R (M) | 50S ribosomal protein L16 | polymer | 138 | 15724.3 | 1 | UniProt (A0A045IWV9) Pfam (PF00252) UniProt (by SIFTS) (P9WHD5) | Mycobacterium tuberculosis | |
| 19 | S (N) | 50S ribosomal protein L17 | polymer | 180 | 19512.3 | 1 | UniProt (A0A045IVA2) Pfam (PF01196) UniProt (by SIFTS) (P9WHD3) | Mycobacterium tuberculosis | |
| 20 | T (O) | 50S ribosomal protein L18 | polymer | 122 | 13211.1 | 1 | UniProt (A0A045JK28) Pfam (PF00861) UniProt (by SIFTS) (P9WHD1) | Mycobacterium tuberculosis | |
| 21 | U (P) | 50S ribosomal protein L19 | polymer | 113 | 13041.1 | 1 | UniProt (A0A045IDD2) Pfam (PF01245) UniProt (by SIFTS) (P9WHC9) | Mycobacterium tuberculosis | |
| 22 | V (Q) | 50S ribosomal protein L20 | polymer | 129 | 14557.8 | 1 | UniProt (A0A045KJ85) Pfam (PF00453) UniProt (by SIFTS) (P9WHC5) | Mycobacterium tuberculosis | |
| 23 | W (R) | LSU ribosomal protein L21p | polymer | 104 | 11173.1 | 1 | UniProt (A0A1N6MHB1) Pfam (PF00829) UniProt (by SIFTS) (P9WHC3) | Mycobacterium tuberculosis | Ribosomal protein L21 (BL20) |
| 24 | X (S) | 50S ribosomal protein L22 | polymer | 197 | 20424.6 | 1 | UniProt (A0A045H760) Pfam (PF00237) UniProt (by SIFTS) (P9WHC1) | Mycobacterium tuberculosis | |
| 25 | Y (T) | 50S ribosomal protein L23 | polymer | 100 | 10976.8 | 1 | UniProt (A0A045J9M3) Pfam (PF00276) UniProt (by SIFTS) (P9WHB9) | Mycobacterium tuberculosis | |
| 26 | Z (U) | 50S ribosomal protein L24 | polymer | 105 | 11500.3 | 1 | UniProt (A0A045IXU4) Pfam (PF00467) Pfam (PF17136) UniProt (by SIFTS) (P9WHB7) | Mycobacterium tuberculosis | |
| 27 | AA (V) | 50S ribosomal protein L25 | polymer | 215 | 22466.2 | 1 | UniProt (A0A045JAK4) Pfam (PF01386) Pfam (PF14693) UniProt (by SIFTS) (P9WHB5) | Mycobacterium tuberculosis | General stress protein CTC |
| 28 | BA (W) | 50S ribosomal protein L27 | polymer | 86 | 8987.3 | 1 | UniProt (A0A045K0G1) Pfam (PF01016) UniProt (by SIFTS) (P9WHB3) | Mycobacterium tuberculosis | |
| 29 | CA (X) | 50S ribosomal protein L28 | polymer | 64 | 6920.1 | 1 | UniProt (A0A045IDB8) Pfam (PF00830) UniProt (by SIFTS) (P0DV54) | Mycobacterium tuberculosis | |
| 30 | DA (Y) | 50S ribosomal protein L29 | polymer | 77 | 8872.0 | 1 | UniProt (A0A045IQ64) Pfam (PF00831) UniProt (by SIFTS) (P9WHA7) | Mycobacterium tuberculosis | |
| 31 | EA (Z) | 50S ribosomal protein L30 | polymer | 65 | 7361.6 | 1 | UniProt (A0A045H4J2) Pfam (PF00327) UniProt (by SIFTS) (P9WHA3) | Mycobacterium tuberculosis | |
| 32 | FA (a) | 16S rRNA | polymer | 1537 | 498260.4 | 1 | GenBank (1050844762) | Mycobacterium tuberculosis | |
| 33 | GA (b) | Capreomycin | polymer | 6 | 670.7 | 1 | NOR (NOR00639) BIRD (PRD_002272) | Streptomyces puniceus | |
| 34 | HA (c) | 30S ribosomal protein S3 | polymer | 274 | 30039.0 | 1 | UniProt (A0A045H4H6) Pfam (PF07650) Pfam (PF00189) UniProt (by SIFTS) (P9WH37) | Mycobacterium tuberculosis | |
| 35 | IA (d) | 30S ribosomal protein S4 | polymer | 201 | 23515.9 | 1 | UniProt (A0A045GRS4) Pfam (PF00163) Pfam (PF01479) UniProt (by SIFTS) (P9WH35) | Mycobacterium tuberculosis | |
| 36 | JA (e) | 30S ribosomal protein S5 | polymer | 220 | 22925.2 | 1 | UniProt (A0A045JKV0) Pfam (PF00333) Pfam (PF03719) UniProt (by SIFTS) (P9WH33) | Mycobacterium tuberculosis | |
| 37 | KA (f) | 30S ribosomal protein S6 | polymer | 96 | 10952.7 | 1 | UniProt (A0A045JVY9) Pfam (PF01250) UniProt (by SIFTS) (P9WH31) | Mycobacterium tuberculosis | |
| 38 | LA (g) | 30S ribosomal protein S7 | polymer | 156 | 17633.4 | 1 | UniProt (A0A045JMN7) Pfam (PF00177) UniProt (by SIFTS) (P9WH29) | Mycobacterium tuberculosis | |
| 39 | MA (h) | 30S ribosomal protein S8 | polymer | 132 | 14432.6 | 1 | UniProt (A0A045IWX2) Pfam (PF00410) UniProt (by SIFTS) (P9WH27) | Mycobacterium tuberculosis | |
| 40 | NA (i) | 30S ribosomal protein S9 | polymer | 151 | 16465.1 | 1 | UniProt (A0A045I839) Pfam (PF00380) UniProt (by SIFTS) (P9WH25) | Mycobacterium tuberculosis | |
| 41 | OA (j) | 30S ribosomal protein S10 | polymer | 101 | 11420.3 | 1 | UniProt (A0A045HTN2) Pfam (PF00338) UniProt (by SIFTS) (P9WH67) | Mycobacterium tuberculosis | |
| 42 | PA (k) | 30S ribosomal protein S11 | polymer | 139 | 14815.9 | 1 | UniProt (A0A045I821) Pfam (PF00411) UniProt (by SIFTS) (P9WH65) | Mycobacterium tuberculosis | |
| 43 | QA (l) | 30S ribosomal protein S12 | polymer | 124 | 13882.3 | 1 | UniProt (M9TET4) Pfam (PF00164) UniProt (by SIFTS) (P9WH63) | Mycobacterium tuberculosis | |
| 44 | RA (m) | 30S ribosomal protein S13 | polymer | 124 | 14383.8 | 1 | UniProt (A0A045GT82) Pfam (PF00416) UniProt (by SIFTS) (P9WH61) | Mycobacterium tuberculosis | |
| 45 | SA (n) | 30S ribosomal protein S14 type Z | polymer | 61 | 6841.2 | 1 | UniProt (A0A045HUG3) Pfam (PF00253) UniProt (by SIFTS) (P9WH57) | Mycobacterium tuberculosis | |
| 46 | TA (o) | 30S ribosomal protein S15 | polymer | 89 | 10500.3 | 1 | UniProt (A0A045JF49) Pfam (PF00312) UniProt (by SIFTS) (P9WH55) | Mycobacterium tuberculosis | |
| 47 | UA (p) | 30S ribosomal protein S16 | polymer | 162 | 17466.1 | 1 | UniProt (A0A045JER3) Pfam (PF00886) UniProt (by SIFTS) (P9WH53) | Mycobacterium tuberculosis | |
| 48 | VA (q) | 30S ribosomal protein S17 | polymer | 135 | 14776.4 | 1 | UniProt (A0A0E9AP91) Pfam (PF00366) UniProt (by SIFTS) (P9WH51) | Mycobacterium tuberculosis | |
| 49 | WA (r) | 30S ribosomal protein S18 | polymer | 84 | 9565.3 | 1 | UniProt (A0A045JW21) Pfam (PF01084) UniProt (by SIFTS) (P9WH49) | Mycobacterium tuberculosis | |
| 50 | XA (s) | 30S ribosomal protein S19 | polymer | 93 | 10830.6 | 1 | UniProt (A0A045IXT2) Pfam (PF00203) UniProt (by SIFTS) (P9WH45) | Mycobacterium tuberculosis | |
| 51 | YA (t) | 30S ribosomal protein S20 | polymer | 86 | 9396.9 | 1 | UniProt (A0A045GXQ2) Pfam (PF01649) UniProt (by SIFTS) (P9WH41) | Mycobacterium tuberculosis | |
| 52 | ZA (x) | Mitochondrial domain of uncharacterised function (DUF1713) | polymer | 33 | 4164.3 | 1 | UniProt (A0A0T5Y2Y4) Pfam (PF08213) UniProt (by SIFTS) (P9WKT5) | Mycobacterium tuberculosis |
Sequence modifications
2: 1 - 47 (UniProt: A0A1L6JUG3)
4: 1 - 37 (UniProt: A0A1L6JSF4)
L: 1 - 146 (UniProt: A0A0T7M0A0)
c: 1 - 274 (UniProt: A0A045H4H6)
j: 1 - 101 (UniProt: A0A045HTN2)
t: 1 - 86 (UniProt: A0A045GXQ2)
| PDB | External Database | Details |
|---|---|---|
| Val 1 | Met 1 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Val 1 | Met 1 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Val 1 | Met 1 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Val 1 | Met 1 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Val 1 | Met 1 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Val 1 | Met 1 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 52 |
| Total formula weight | 2231037.8 | |
| All* | Total formula weight | 2231037.8 |
