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5V8V

Crystal Structure of Human Renin in Complex with a biphenylpipderidinylcarbinol

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Reninpolymer33736939.62UniProt (P00797)
Pfam (PF00026)
Homo sapiens (Human)Angiotensinogenase
2C, F
(A, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
3D, E, G, H
(A, B)
methyl [(4S)-4-(3'-ethyl-6-fluoro[1,1'-biphenyl]-2-yl)-4-hydroxy-4-{(3R)-1-[4-(methylamino)butanoyl]piperidin-3-yl}butyl]carbamatenon-polymer527.74Chemie (90D)
4I, J
(A, B)
waterwater18.069Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight73879.2
Non-Polymers*Number of molecules6
Total formula weight2553.1
All*Total formula weight76432.3
*Water molecules are not included.

238268

PDB entries from 2025-07-02

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