5V8Q
Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs): Part III
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Androgen receptor | polymer | 249 | 28988.0 | 1 | UniProt (P10275) Pfam (PF00104) | Homo sapiens (Human) | Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4 |
| 2 | B, C, D (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 3 | E (A) | 4-[(2S,3S)-2-ethyl-3-hydroxy-5-oxopyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile | non-polymer | 298.3 | 1 | Chemie (97A) | |||
| 4 | F (A) | water | water | 18.0 | 159 | Chemie (HOH) |
Sequence modifications
A: 671 - 919 (UniProt: P10275)
| PDB | External Database | Details |
|---|---|---|
| Ala 845 | Lys 314 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28988.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 574.5 | |
| All* | Total formula weight | 29562.5 |
