5V46
Crystal structure of the I113M, F270M, K291M, L308M mutant of SR1 domain of human sacsin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Sacsin | polymer | 253 | 28846.5 | 2 | UniProt (Q9NZJ4) | Homo sapiens (Human) | DnaJ homolog subfamily C member 29,DNAJC29 |
| 2 | C, D (A, B) | water | water | 18.0 | 203 | Chemie (HOH) |
Sequence modifications
A, B: 89 - 336 (UniProt: Q9NZJ4)
| PDB | External Database | Details |
|---|---|---|
| Gly 84 | - | expression tag |
| Pro 85 | - | expression tag |
| Leu 86 | - | expression tag |
| Gly 87 | - | expression tag |
| Ser 88 | - | expression tag |
| Mse 113 | Ile 113 | engineered mutation |
| Mse 270 | Phe 270 | engineered mutation |
| Mse 291 | Lys 291 | engineered mutation |
| Mse 308 | Leu 308 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57693.0 | |
| All* | Total formula weight | 57693.0 |
