5V2P

CaV beta2a subunit: CaV1.2 AID-CAP complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Voltage-dependent L-type calcium channel subunit beta-2	polymer	347	39186.6	1	UniProt (Q8VGC3) Pfam (PF12052) Pfam (PF00625) In PDB	Rattus norvegicus (Rat)	CAB2, Calcium channel voltage-dependent subunit beta 2
2	B	Voltage-dependent L-type calcium channel subunit alpha-1C	polymer	19	2185.5	1	UniProt (Q13936) In PDB	Homo sapiens	Calcium channel, L type,alpha-1 polypeptide, isoform 1, cardiac muscle, Voltage-gated calcium channel subunit alpha Cav1.2
3	A	NICKEL (II) ION	non-polymer		58.7	1	Chemie (NI)
4	A	PENTAETHYLENE GLYCOL	non-polymer		238.3	2	Chemie (1PE)
5	B	1,3-bis(bromomethyl)benzene	non-polymer		264.0	1	Chemie (8VY)
6		water	water		18.0	374	Chemie (HOH)

Sequence modifications

A: 67 - 252 (UniProt: Q8VGC3)

PDB	External Database	Details
Ser 82	-	insertion

A: 254 - 476 (UniProt: Q8VGC3)

PDB	External Database	Details
Ser 253	-	linker

B: 427 - 445 (UniProt: Q13936)

PDB	External Database	Details
Cys 427	Lys 427	engineered mutation
Ser 428	Gln 428	engineered mutation
Pro 429	Gln 429	engineered mutation
Cys 432	Glu 432	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	41372.1
Non-Polymers*	Number of molecules	4
	Total formula weight	799.2
All*	Total formula weight	42171.3

*Water molecules are not included.