5V2N
Crystal Structure of APO Human SETD8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | N-lysine methyltransferase KMT5A | polymer | 165 | 18500.8 | 1 | UniProt (Q9NQR1) Pfam (PF00856) | Homo sapiens (Human) | H4-K20-HMTase KMT5A,Histone-lysine N-methyltransferase KMT5A,Lysine N-methyltransferase 5A,Lysine-specific methylase 5A,PR/SET domain-containing protein 07,PR/SET07,SET domain-containing protein 8 |
| 2 | B, C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 3 | E (A) | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence modifications
A: 190 - 352 (UniProt: Q9NQR1)
| PDB | External Database | Details |
|---|---|---|
| Gly 188 | - | expression tag |
| Gly 189 | - | expression tag |
| Ala 256 | Lys 297 | conflict |
| Ala 257 | Lys 298 | conflict |
| Ala 259 | Glu 300 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18500.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 186.2 | |
| All* | Total formula weight | 18687.0 |
