5V2I
Crystal structure of a mutant glycosylasparaginase (G172D) that causes the genetic disease Aspartylglucosaminuria
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Glycosylasparaginase | polymer | 295 | 32237.7 | 2 | UniProt (A0A1E3DWI1) Pfam (PF01112) UniProt (by SIFTS) (Q47898) In PDB | Elizabethkingia meningoseptica | |
| 2 | water | water | 18.0 | 332 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 295 (UniProt: A0A1E3DWI1)
| PDB | External Database | Details |
|---|---|---|
| Thr 2 | Val 38 | conflict |
| His 16 | Gln 52 | conflict |
| Ala 126 | Pro 162 | conflict |
| Asp 172 | Gly 208 | engineered mutation |
| Asn 244 | Lys 280 | conflict |
| Thr 289 | Lys 325 | conflict |
| Gly 291 | Glu 327 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64475.3 | |
| All* | Total formula weight | 64475.3 |
