5V2I

Crystal structure of a mutant glycosylasparaginase (G172D) that causes the genetic disease Aspartylglucosaminuria

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glycosylasparaginase	polymer	295	32237.7	2	UniProt (A0A1E3DWI1) UniProt (by SIFTS) (Q47898)	Elizabethkingia meningoseptica
2	C, D (A, B)	water	water		18.0	332	Chemie (HOH)

Sequence modifications

A, B: 1 - 295 (UniProt: A0A1E3DWI1)

PDB	External Database	Details
Thr 2	Val 38	conflict
His 16	Gln 52	conflict
Ala 126	Pro 162	conflict
Asp 172	Gly 208	engineered mutation
Asn 244	Lys 280	conflict
Thr 289	Lys 325	conflict
Gly 291	Glu 327	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	64475.3
All*	Total formula weight	64475.3

*Water molecules are not included.