5V18
Structure of PHD2 in complex with 1,2,4-Triazolo-[1,5-a]pyridine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Egl nine homolog 1 | polymer | 239 | 26693.4 | 1 | UniProt (Q9GZT9) Pfam (PF13640) | Homo sapiens (Human) | Hypoxia-inducible factor prolyl hydroxylase 2,HPH-2,Prolyl hydroxylase domain-containing protein 2,PHD2,SM-20 |
| 2 | B, C (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | D (A) | 4-([1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile | non-polymer | 220.2 | 1 | Chemie (8UY) | |||
| 4 | E (A) | FE (II) ION | non-polymer | 55.8 | 1 | Chemie (FE2) | |||
| 5 | F (A) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A: 181 - 416 (UniProt: Q9GZT9)
| PDB | External Database | Details |
|---|---|---|
| Gly 178 | - | expression tag |
| Gly 179 | - | expression tag |
| Ser 180 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26693.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 468.2 | |
| All* | Total formula weight | 27161.6 |
