5V0L
Crystal structure of the AHR-ARNT heterodimer in complex with the DRE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Aryl hydrocarbon receptor nuclear translocator | polymer | 279 | 31028.1 | 1 | UniProt (P27540) Pfam (PF00010) Pfam (PF00989) In PDB | Homo sapiens (Human) | ARNT protein,Class E basic helix-loop-helix protein 2,bHLHe2,Dioxin receptor,nuclear translocator,Hypoxia-inducible factor 1-beta,HIF1-beta |
| 2 | B | Aryl hydrocarbon receptor | polymer | 241 | 27151.7 | 1 | UniProt (P30561) Pfam (PF00010) Pfam (PF00989) In PDB | Mus musculus (Mouse) | AhR |
| 3 | C | DNA (5'-D(P*GP*GP*AP*TP*TP*GP*CP*GP*TP*GP*AP*GP*AP*AP*CP*TP*G)-3') | polymer | 17 | 5307.4 | 1 | Homo sapiens | ||
| 4 | D | DNA (5'-D(P*AP*GP*TP*TP*CP*TP*CP*AP*CP*GP*CP*AP*AP*T)-3') | polymer | 14 | 4239.8 | 1 | Homo sapiens | ||
| 5 | A, B | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 6 | B, C | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) |
Sequence modifications
A: 70 - 346 (UniProt: P27540)
B: 29 - 267 (UniProt: P30561)
| PDB | External Database | Details |
|---|---|---|
| Gly 68 | - | expression tag |
| Ser 69 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 27 | - | expression tag |
| Ser 28 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 67727.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 596.5 | |
| All* | Total formula weight | 68323.5 |
