5UZW

PCY1 G696Insertion Variant in Complex with Follower Peptide and the Covalent Inhibitor ZPP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G (A, B, C, D)	Peptide cyclase 1	polymer	751	85657.8	4	UniProt (R4P353) Pfam (PF02897) Pfam (PF00326)	Vaccaria hispanica
2	B, D, F, H (E, F, G, H)	Presegetalin A1	polymer	6	557.6	4	UniProt (F6LNL5)	Vaccaria hispanica
3	I, K, N, O (A, B, C, D)	N-BENZYLOXYCARBONYL-L-PROLYL-L-PROLINAL	non-polymer		330.4	4	BIRD (PRD_000692) Chemie (ZPR)
4	J, L, M (A, B)	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
5	P, Q, R, S (A, B, C, D)	water	water		18.0	61	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 725 (UniProt: R4P353)

PDB	External Database	Details
Met -25	-	initiating methionine
Ser -24	-	expression tag
Tyr -23	-	expression tag
Tyr -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
Leu -15	-	expression tag
Glu -14	-	expression tag
Ser -13	-	expression tag
Thr -12	-	expression tag
Ser -11	-	expression tag
Leu -10	-	expression tag
Tyr -9	-	expression tag
Lys -8	-	expression tag
Lys -7	-	expression tag
Ala -6	-	expression tag
Gly -5	-	expression tag
Ser -4	-	expression tag
Glu -3	-	expression tag
Phe -2	-	expression tag
Ala -1	-	expression tag
Leu 0	-	expression tag
Gly 696	-	insertion

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	344861.6
Non-Polymers*	Number of molecules	7
	Total formula weight	1441.7
All*	Total formula weight	346303.3

*Water molecules are not included.