5UZK
Crystal Structure of PKA bound to an pyrrolo pyridine inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 351 | 40808.6 | 1 | UniProt (P17612) Pfam (PF00069) | Homo sapiens (Human) | PKA C-alpha |
| 2 | B (I) | cAMP-dependent protein kinase inhibitor alpha | polymer | 18 | 1973.2 | 1 | UniProt (P61926) | Oryctolagus cuniculus | PKI-alpha,cAMP-dependent protein kinase inhibitor,muscle/brain isoform |
| 3 | C (A) | 2-{3-[3-(piperidin-4-yl)propoxy]phenyl}-N-[4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-1,3-thiazol-2-yl]acetamide | non-polymer | 475.6 | 1 | Chemie (504) | |||
| 4 | D, E (A, I) | water | water | 18.0 | 275 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42781.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 475.6 | |
| All* | Total formula weight | 43257.4 |
