5UZE
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P182
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase | polymer | 363 | 38441.3 | 4 | UniProt (A0A0H2YRZ7) Pfam (PF00478) In PDB | Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) | IMPDH |
2 | A, B, C, D | INOSINIC ACID | non-polymer | 348.2 | 4 | Chemie (IMP) | |||
3 | A, B, C, D | N-{4-chloro-3-[4-(trifluoromethyl)-1,3-thiazol-2-yl]phenyl}-N'-(2-{3-[(1E)-N-hydroxyethanimidoyl]phenyl}propan-2-yl)urea | non-polymer | 496.9 | 4 | Chemie (8L1) | |||
4 | A, B | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
5 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
6 | water | water | 18.0 | 156 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 88 (UniProt: A0A0H2YRZ7)
A, B, C, D: 216 - 484 (UniProt: A0A0H2YRZ7)
PDB | External Database | Details |
---|---|---|
Ser -2 | - | expression tag |
Asn -1 | - | expression tag |
Ala 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ser 89 | - | linker |
Gly 90 | - | linker |
Gly 91 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 153765.1 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 3550.8 | |
All* | Total formula weight | 157315.9 |