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5UY9

Prolyl isomerase Pin1 R14A mutant bound with Brd4 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1polymer16318185.21UniProt (Q13526)
Pfam (PF00397)
Pfam (PF00639)
Homo sapiens (Human)Peptidyl-prolyl cis-trans isomerase Pin1,PPIase Pin1,Rotamase Pin1
2B
(B)
Brd4 peptidepolymer7859.81Homo sapiens
3C
(A)
2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOLnon-polymer354.41Chemie (PE4)
4D, E
(A, B)
SULFATE IONnon-polymer96.12Chemie (SO4)
5F, G
(A, B)
waterwater18.080Chemie (HOH)
Sequence modifications
A: 1 - 163 (UniProt: Q13526)
PDBExternal DatabaseDetails
Ala 14Arg 14engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight19045.0
Non-Polymers*Number of molecules3
Total formula weight546.6
All*Total formula weight19591.6
*Water molecules are not included.

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PDB entries from 2025-12-10

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