5UWL
Matrix metalloproteinase-13 complexed with selective inhibitor compound (S)-17a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Collagenase 3 | polymer | 172 | 19366.6 | 2 | UniProt (P45452) Pfam (PF00413) In PDB | Homo sapiens (Human) | Matrix metalloproteinase-13,MMP-13 |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 3 | A, B | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 4 | A, B | (S)-N-(3-methyl-1-(methylamino)-1-oxobutan-2-yl)-5-(4-(((4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[d]pyrimidin-2-yl)thio)methyl)phenyl)furan-2-carboxamide | non-polymer | 480.6 | 2 | Chemie (8OJ) | |||
| 5 | water | water | 18.0 | 62 | Chemie (HOH) |
Sequence modifications
A, B: 104 - 274 (UniProt: P45452)
| PDB | External Database | Details |
|---|---|---|
| Met 103 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38733.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1357.8 | |
| All* | Total formula weight | 40090.9 |
