5UW0
Activated state yGsy2p in complex with UDP-2-fluoro-2-deoxy-glucose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glycogen [starch] synthase isoform 2 | polymer | 720 | 81818.6 | 4 | UniProt (P27472) Pfam (PF05693) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | |
| 2 | E, G, K (A, B, D) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 3 | Chemie (UDP) PubChem (1158) PubChem (6031) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (53486216) PubChem (60098857) PubChem (57448939) PubChem (3084486) PubChem (91746160) PubChem (6101632) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (93088131) PubChem (93630083) PubChem (6604175) PubChem (11811538) PubChem (12049241) | |||
| 3 | F, H, J, L (A, B, C, D) | 6-O-phosphono-alpha-D-glucopyranose | non-polymer | 260.1 | 4 | Chemie (G6P) | |||
| 4 | I (C) | URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE | non-polymer | 568.3 | 1 | Chemie (U2F) | |||
| 5 | M (C) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 700 (UniProt: P27472)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | initiating methionine |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Gln 169 | Glu 169 | engineered mutation |
| Ser 535 | Ala 535 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 327274.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2821.3 | |
| All* | Total formula weight | 330095.8 |
