5URN

NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and the transactivation domain 1 of p65

Replaces:  2N22

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	RNA polymerase II transcription factor B subunit 1	polymer	115	12903.7	1	UniProt (P32776) Pfam (PF08567)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	General transcription and DNA repair factor IIH subunit TFB1,TFIIH subunit TFB1,RNA polymerase II transcription factor B 73 kDa subunit,RNA polymerase II transcription factor B p73 subunit
2	B (B)	Transcription factor p65	polymer	33	3378.6	1	UniProt (Q04206)	Homo sapiens (Human)	Nuclear factor NF-kappa-B p65 subunit,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3

Sequence modifications

A: 2 - 115 (UniProt: P32776)

PDB	External Database	Details
Pro 1	-	expression tag

B: 521 - 551 (UniProt: Q04206)

PDB	External Database	Details
Gly 519	-	expression tag
Ser 520	-	expression tag
Tyr 523	Leu 523	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	16282.3
All*	Total formula weight	16282.3

*Water molecules are not included.