5URM
Crystal structure of human BRR2 in complex with T-1206548
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | U5 small nuclear ribonucleoprotein 200 kDa helicase | polymer | 1738 | 198582.6 | 2 | UniProt (O75643) Pfam (PF00270) Pfam (PF00271) Pfam (PF02889) | Homo sapiens (Human) | Activating signal cointegrator 1 complex subunit 3-like 1,BRR2 homolog,U5 snRNP-specific 200 kDa protein,U5-200KD |
| 2 | C, D (A, B) | 3-(5-{[(2R)-5-amino-2-cyclohexyl-7-oxo-2,3-dihydro-7H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-6-yl]methyl}furan-2-yl)benzoic acid | non-polymer | 452.5 | 2 | Chemie (8LV) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 102 | Chemie (HOH) |
Sequence modifications
A, B: 395 - 2129 (UniProt: O75643)
| PDB | External Database | Details |
|---|---|---|
| Gly 392 | - | expression tag |
| Gly 393 | - | expression tag |
| Ser 394 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 397165.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 905.1 | |
| All* | Total formula weight | 398070.2 |
