5UQU
Crystal structure of mutant 2-methylcitrate synthase (mcsAG352A) from Aspergillus fumigatus
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 2-methylcitrate synthase, mitochondrial | polymer | 441 | 48571.5 | 2 | UniProt (Q50I20) Pfam (PF00285) | Neosartorya fumigata | Methylcitrate synthase,(2S,3S)-2-methylcitrate synthase,Citrate synthase 1 |
| 2 | C, E, F (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | D (A) | OXALOACETATE ION | non-polymer | 131.1 | 1 | Chemie (OAA) | |||
| 4 | G (B) | COENZYME A | non-polymer | 767.5 | 1 | Chemie (COA) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 749 | Chemie (HOH) |
Sequence modifications
A, B: 29 - 465 (UniProt: Q50I20)
| PDB | External Database | Details |
|---|---|---|
| Ser 25 | - | expression tag |
| Gly 26 | - | expression tag |
| Ser 27 | - | expression tag |
| Gly 28 | - | expression tag |
| Ala 352 | Gly 352 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 97142.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1186.8 | |
| All* | Total formula weight | 98329.7 |
