5UQ3
Crystal structure of human Cdk2-Spy1-P27 ternary complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cyclin-dependent kinase 2 | polymer | 301 | 34309.8 | 1 | UniProt (P24941) Pfam (PF00069) | Homo sapiens (Human) | Cell division protein kinase 2,p33 protein kinase |
| 2 | B (B) | Speedy protein A | polymer | 160 | 19312.2 | 1 | UniProt (Q5MJ70) Pfam (PF11357) | Homo sapiens (Human) | Rapid inducer of G2/M progression in oocytes A,hSpy/Ringo A,Speedy-1,Spy1 |
| 3 | C (C) | Cyclin-dependent kinase inhibitor 1B | polymer | 201 | 22441.7 | 1 | UniProt (P46527) Pfam (PF02234) | Homo sapiens (Human) | Cyclin-dependent kinase inhibitor p27,p27Kip1 |
Sequence modifications
A: 1 - 298 (UniProt: P24941)
B: 61 - 213 (UniProt: Q5MJ70)
C: 507 - 704 (UniProt: P46527)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 54 | - | expression tag |
| Ala 55 | - | expression tag |
| Met 56 | - | expression tag |
| Asp 57 | - | expression tag |
| Pro 58 | - | expression tag |
| Glu 59 | - | expression tag |
| Phe 60 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 504 | - | expression tag |
| Glu 505 | - | expression tag |
| Phe 506 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 76063.7 | |
| All* | Total formula weight | 76063.7 |
