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5UQ1

Crystal structure of human Cdk2-Spy1 complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
Cyclin-dependent kinase 2polymer30134309.82UniProt (P24941)
Pfam (PF00069)
Homo sapiens (Human)Cell division protein kinase 2,p33 protein kinase
2B, D
(B, D)
Speedy protein Apolymer16019312.22UniProt (Q5MJ70)
Pfam (PF11357)
Homo sapiens (Human)Rapid inducer of G2/M progression in oocytes A,hSpy/Ringo A,Speedy-1,Spy1
Sequence modifications
A, C: 1 - 298 (UniProt: P24941)
PDBExternal DatabaseDetails
Gly -2-expression tag
Glu -1-expression tag
Phe 0-expression tag
B, D: 61 - 213 (UniProt: Q5MJ70)
PDBExternal DatabaseDetails
Gly 54-expression tag
Ala 55-expression tag
Met 56-expression tag
Asp 57-expression tag
Pro 58-expression tag
Glu 59-expression tag
Phe 60-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight107244.1
All*Total formula weight107244.1
*Water molecules are not included.

226707

PDB entries from 2024-10-30

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