5UP9
Crystal Structure of Zn-bound Human Heavy-Chain ferritin variant 122H-delta C-star with para-xylenedihydroxamate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Ferritin heavy chain | polymer | 182 | 21122.3 | 6 | UniProt (P02794) Pfam (PF00210) | Homo sapiens (Human) | Ferritin H subunit,Cell proliferation-inducing gene 15 protein |
| 2 | AA, BA, G, H, I... (C, A, D, E, B...) | ZINC ION | non-polymer | 65.4 | 19 | Chemie (ZN) | |||
| 3 | K, KA, L, LA, MA (A, D) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 5 | Chemie (PGE) | |||
| 4 | CA, DA, EA, FA, GA... (C, A, D, B, E...) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 19 | Chemie (PEG) | |||
| 5 | W (B) | 2,2'-(1,4-phenylene)bis(N-hydroxyacetamide) | non-polymer | 224.2 | 1 | Chemie (BYX) | |||
| 6 | AB, BB, CB, DB, YA... (C, D, E, F, A...) | water | water | 18.0 | 1094 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 182 (UniProt: P02794)
| PDB | External Database | Details |
|---|---|---|
| Gln 86 | Lys 87 | engineered mutation |
| Glu 90 | Cys 91 | engineered mutation |
| Ala 102 | Cys 103 | engineered mutation |
| His 122 | Thr 123 | engineered mutation |
| Ala 130 | Cys 131 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 126733.7 | |
| Non-Polymers* | Number of molecules | 44 |
| Total formula weight | 4234.1 | |
| All* | Total formula weight | 130967.9 |
