5UOD
Structure of bovine endothelial nitric oxide synthase heme domain in complex with 3-[(2-Amino-4-methylquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Nitric oxide synthase, endothelial | polymer | 443 | 49727.0 | 2 | UniProt (P29473) Pfam (PF02898) In PDB | Bos taurus (Bovine) | Constitutive NOS,cNOS,EC-NOS,Endothelial NOS,eNOS,NOS type III,NOSIII |
| 2 | A, B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | A, B | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 2 | Chemie (H4B) | |||
| 4 | A, B | 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-[(methylamino)methyl]benzonitrile | non-polymer | 332.4 | 2 | Chemie (8EY) | |||
| 5 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 7 | water | water | 18.0 | 474 | Chemie (HOH) |
Sequence modifications
A, B: 40 - 482 (UniProt: P29473)
| PDB | External Database | Details |
|---|---|---|
| Arg 100 | Cys 100 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 99454.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2629.9 | |
| All* | Total formula weight | 102083.9 |
