5UOA
Structure of human endothelial nitric oxide synthase heme domain in complex with 3-[(2-Amino-4-methylquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nitric oxide synthase, endothelial | polymer | 440 | 49345.8 | 2 | UniProt (P29474) Pfam (PF02898) | Homo sapiens (Human) | Constitutive NOS,cNOS,EC-NOS,Endothelial NOS,eNOS,NOS type III,NOSIII |
| 2 | C, N (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | D, E, O, P (A, B) | 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-[(methylamino)methyl]benzonitrile | non-polymer | 332.4 | 4 | Chemie (8EY) | |||
| 4 | F, G, Q, R, S... (A, B) | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 8 | Chemie (BTB) | |||
| 5 | H, K, L (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 6 | I (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | J, W (A, B) | GADOLINIUM ATOM | non-polymer | 157.3 | 2 | Chemie (GD) | |||
| 8 | M, X (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 9 | Y, Z (A, B) | water | water | 18.0 | 58 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 98691.5 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 4910.2 | |
| All* | Total formula weight | 103601.8 |
