5UO8
Structure of human endothelial nitric oxide synthase heme domain in complex with 3-[(2-aminoquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Nitric oxide synthase, endothelial | polymer | 440 | 49345.8 | 4 | UniProt (P29474) Pfam (PF02898) | Homo sapiens (Human) | Constitutive NOS, cNOS, EC-NOS, Endothelial NOS, eNOS, NOS type III, NOSIII |
| 2 | AA, E, M, S (D, A, B, C) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 3 | BA, F, N, T (D, A, B, C) | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 4 | Chemie (H4B) | |||
| 4 | CA, G, O, U (D, A, B, C) | 3-[(2-aminoquinolin-7-yl)methoxy]-5-[(methylamino)methyl]benzonitrile | non-polymer | 318.4 | 4 | Chemie (8EV) | |||
| 5 | DA, EA, H, I, P... (D, A, B, C) | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 8 | Chemie (BTB) | |||
| 6 | J, X (A, C) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 7 | K, Y (A, C) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 8 | FA, L, R, Z (D, A, B, C) | GADOLINIUM ATOM | non-polymer | 157.3 | 4 | Chemie (GD) | |||
| 9 | GA, HA, IA, JA (A, B, C, D) | water | water | 18.0 | 325 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 197383.1 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 7322.4 | |
| All* | Total formula weight | 204705.4 |
