5UNH
Synchrotron structure of human angiotensin II type 2 receptor in complex with compound 2 (N-[(furan-2-yl)methyl]-N-(4-oxo-2-propyl-3-{[2'-(2H-tetrazol-5-yl)[1,1'- biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)benzamide)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Soluble cytochrome b562,Type-2 angiotensin II receptor | polymer | 411 | 46506.5 | 2 | UniProt (P0ABE7) UniProt (P50052) Pfam (PF07361) Pfam (PF00001) In PDB | Escherichia coli | Cytochrome b-562,Angiotensin II type-2 receptor,AT2 |
2 | A, B | N-[(furan-2-yl)methyl]-N-(4-oxo-2-propyl-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)benzamide | non-polymer | 621.7 | 2 | Chemie (8EM) |
Sequence modifications
A, B: 1001 - 1106 (UniProt: P0ABE7)
A, B: 35 - 335 (UniProt: P50052)
PDB | External Database | Details |
---|---|---|
Trp 1007 | Met 29 | engineered mutation |
Ile 1102 | His 124 | engineered mutation |
Leu 1106 | Arg 128 | engineered mutation |
Gly 1107 | - | linker |
Ser 1108 | - | linker |
Gly 1109 | - | linker |
Ser 1110 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 93013.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1243.4 | |
All* | Total formula weight | 94256.4 |