5UNF
XFEL structure of human angiotensin II type 2 receptor (Monoclinic form) in complex with compound 1 (N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl])
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Chimera protein of Type-2 angiotensin II receptor and Soluble cytochrome b562 | polymer | 411 | 46506.5 | 2 | UniProt (P0ABE7) UniProt (P50052) Pfam (PF07361) Pfam (PF00001) In PDB | Escherichia coli | Cytochrome b-562,Angiotensin II type-2 receptor,AT2 |
2 | A, B | N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)thiophene-2-carboxamide | non-polymer | 623.7 | 2 | Chemie (8ES) |
Sequence modifications
A, B: 1001 - 1106 (UniProt: P0ABE7)
A, B: 35 - 335 (UniProt: P50052)
PDB | External Database | Details |
---|---|---|
Trp 1007 | Met 29 | engineered mutation |
Ile 1102 | His 124 | engineered mutation |
Leu 1106 | Arg 128 | engineered mutation |
Gly 1107 | - | linker |
Ser 1108 | - | linker |
Gly 1109 | - | linker |
Ser 1110 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 93013.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1247.5 | |
All* | Total formula weight | 94260.5 |