5UN8
Crystal Structure of human O-GlcNAcase in complex with glycopeptide p53
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Protein O-GlcNAcase | polymer | 504 | 57822.6 | 4 | UniProt (O60502) Pfam (PF07555) | Homo sapiens (Human) | OGA,Beta-N-acetylglucosaminidase,Beta-N-acetylhexosaminidase,Beta-hexosaminidase,Meningioma-expressed antigen 5,N-acetyl-beta-D-glucosaminidase,N-acetyl-beta-glucosaminidase,Nuclear cytoplasmic O-GlcNAcase and acetyltransferase,NCOAT |
| 2 | E, F, G, H (E, F, G, H) | P53 peptide | polymer | 11 | 1196.3 | 4 | UniProt (by SIFTS) (P04637) | Homo sapiens | |
| 3 | I, J, K, L (E, F, G, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 4 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 1232 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 60 - 542 (UniProt: O60502)
A, B, C, D: 553 - 704 (UniProt: O60502)
| PDB | External Database | Details |
|---|---|---|
| His 59 | - | expression tag |
| Asn 175 | Asp 175 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 543 | - | linker |
| Gly 544 | - | linker |
| Gly 545 | - | linker |
| Gly 546 | - | linker |
| Ser 547 | - | linker |
| Gly 548 | - | linker |
| Gly 549 | - | linker |
| Gly 550 | - | linker |
| Gly 551 | - | linker |
| Ser 552 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 236075.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 236960.4 |
