5UMY

Crystal structure of TnmS3 in complex with tiancimycin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glyoxalase/bleomycin resisance protein/dioxygenase	polymer	140	15152.9	2	UniProt (A0A125SA29) Pfam (PF00903)	Streptomyces sp. CB03234
2	C, D (A)	(1aS,11S,11aR,14Z,18R)-3,8,18-trihydroxy-11a-[(1R)-1-hydroxyethyl]-7-methoxy-11,11a-dihydro-4H-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinoline-4,9(10H)-dione	non-polymer		485.4	2	Chemie (TNN)
3	E, F (A, B)	water	water		18.0	233	Chemie (HOH)

Sequence modifications

A, B: 1 - 124 (UniProt: A0A125SA29)

PDB	External Database	Details
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	30305.8
Non-Polymers*	Number of molecules	2
	Total formula weight	970.9
All*	Total formula weight	31276.7

*Water molecules are not included.