5ULS

Structure of GRP94 in the active conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Endoplasmin	polymer	691	79506.3	2	UniProt (P41148) Pfam (PF13589) Pfam (PF00183)	Canis lupus familiaris (Dog)	94 kDa glucose-regulated protein,GRP-94,Heat shock protein 90 kDa beta member 1
2	C, D (A, B)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	2	Chemie (ANP)
3	E, F (A, B)	water	water		18.0	190	Chemie (HOH)

Sequence modifications

A, B: 48 - 286 (UniProt: P41148)

PDB	External Database	Details
Met 27	-	initiating methionine
Gly 28	-	expression tag
Ser 29	-	expression tag
Ser 30	-	expression tag
His 31	-	expression tag
His 32	-	expression tag
His 33	-	expression tag
His 34	-	expression tag
His 35	-	expression tag
His 36	-	expression tag
Ser 37	-	expression tag
Ser 38	-	expression tag
Gly 39	-	expression tag
Leu 40	-	expression tag
Val 41	-	expression tag
Pro 42	-	expression tag
Arg 43	-	expression tag
Gly 44	-	expression tag
Ser 45	-	expression tag
His 46	-	expression tag
Met 47	-	expression tag

A, B: 328 - 754 (UniProt: P41148)

PDB	External Database	Details
Gly 287	-	linker
Gly 288	-	linker
Gly 326	-	linker
Gly 327	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	159012.5
Non-Polymers*	Number of molecules	2
	Total formula weight	1012.4
All*	Total formula weight	160024.9

*Water molecules are not included.