5UKW
Crystal structure of human Glucose 6-phosphate Dehydrogenase mutant (A277C) complexed with G6P
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Glucose-6-phosphate 1-dehydrogenase | polymer | 488 | 56201.9 | 1 | UniProt (P11413) Pfam (PF00479) Pfam (PF02781) In PDB | Homo sapiens (Human) | G6PD |
| 2 | A | 6-O-phosphono-beta-D-glucopyranose | non-polymer | 260.1 | 1 | Chemie (BG6) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 20 | Chemie (HOH) |
Sequence modifications
A: 29 - 511 (UniProt: P11413)
| PDB | External Database | Details |
|---|---|---|
| Gly 24 | - | expression tag |
| Gly 25 | - | expression tag |
| Ser 26 | - | expression tag |
| Glu 27 | - | expression tag |
| Phe 28 | - | expression tag |
| Cys 277 | Ala 307 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 56201.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 352.2 | |
| All* | Total formula weight | 56554.2 |
