5UI1
Crystal Structure of Human Protein Phosphatase 5C (PP5C) in complex with a triazole inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Serine/threonine-protein phosphatase 5 | polymer | 333 | 37887.0 | 4 | UniProt (P53041) Pfam (PF08321) Pfam (PF00149) | Homo sapiens (Human) | PP5,Protein phosphatase T,PPT |
| 2 | E, F, H, I, K... (A, B, C, D) | MANGANESE (II) ION | non-polymer | 54.9 | 8 | Chemie (MN) | |||
| 3 | G, J, M, P (A, B, C, D) | 5-phenyl-1H-1,2,3-triazole-4-carboxylic acid | non-polymer | 189.2 | 4 | Chemie (8D4) | |||
| 4 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 358 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 169 - 499 (UniProt: P53041)
| PDB | External Database | Details |
|---|---|---|
| Gly 167 | - | expression tag |
| Ala 168 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 151548.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1196.2 | |
| All* | Total formula weight | 152744.3 |
