5UFQ
K-RasG12D(GNP)/R11.1.6 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | GTPase KRas | polymer | 166 | 18942.3 | 2 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | C, D (C, D) | R11.1.6 | polymer | 61 | 7258.3 | 2 | Sulfolobus solfataricus | ||
| 3 | E, K (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 2 | Chemie (GNP) | |||
| 4 | F, L (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | G, H, M, P (A, B, D) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 6 | I, N (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 7 | J, O (A, B) | CADMIUM ION | non-polymer | 112.4 | 2 | Chemie (CD) | |||
| 8 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 114 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 166 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Asp 12 | Gly 12 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 52401.3 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1539.8 | |
| All* | Total formula weight | 53941.1 |
