5UAT
Structure of human PYCR-1 complexed with NADPH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Pyrroline-5-carboxylate reductase 1, mitochondrial | polymer | 322 | 34043.2 | 5 | UniProt (P32322) Pfam (PF03807) Pfam (PF14748) | Homo sapiens (Human) | P5CR 1 |
| 2 | F, G, I, K (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | H, L (C, E) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 4 | J (C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | M, N, O, P, Q (A, B, C, D, E) | water | water | 18.0 | 557 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 300 (UniProt: P32322)
| PDB | External Database | Details |
|---|---|---|
| Met -21 | - | initiating methionine |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| Ser -14 | - | expression tag |
| Ser -13 | - | expression tag |
| Gly -12 | - | expression tag |
| Val -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Leu -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Thr -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 170215.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1981.2 | |
| All* | Total formula weight | 172197.0 |
