5U9M

Copper-Zinc Superoxide Dismutase is Activated through a Sulfenic Acid Intermediate at a Copper-ion Entry Site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Superoxide dismutase [Cu-Zn]	polymer	153	15836.6	2	UniProt (P00441) Pfam (PF00080) In PDB	Homo sapiens (Human)	Superoxide dismutase 1,hSod1
2	B, D	Superoxide dismutase 1 copper chaperone	polymer	248	27028.5	2	UniProt (P40202) Pfam (PF00403) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
3	A, B, C	ZINC ION	non-polymer		65.4	3	Chemie (ZN)
4		water	water		18.0	120	Chemie (HOH)

Sequence modifications

A, C: 1 - 153 (UniProt: P00441)

PDB	External Database	Details
Arg 46	His 47	engineered mutation
Gln 48	His 49	engineered mutation

B, D: 2 - 249 (UniProt: P40202)

PDB	External Database	Details
Ala 238	Glu 238	engineered mutation
Ala 239	Glu 239	engineered mutation
Ala 240	Arg 240	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	85730.2
Non-Polymers*	Number of molecules	3
	Total formula weight	196.2
All*	Total formula weight	85926.4

*Water molecules are not included.