5U9M
Copper-Zinc Superoxide Dismutase is Activated through a Sulfenic Acid Intermediate at a Copper-ion Entry Site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Superoxide dismutase [Cu-Zn] | polymer | 153 | 15836.6 | 2 | UniProt (P00441) Pfam (PF00080) | Homo sapiens (Human) | Superoxide dismutase 1,hSod1 |
| 2 | B, D (B, D) | Superoxide dismutase 1 copper chaperone | polymer | 248 | 27028.5 | 2 | UniProt (P40202) Pfam (PF00403) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | |
| 3 | E, F, G (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | H, I, J, K (A, B, C, D) | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 153 (UniProt: P00441)
B, D: 2 - 249 (UniProt: P40202)
| PDB | External Database | Details |
|---|---|---|
| Arg 46 | His 47 | engineered mutation |
| Gln 48 | His 49 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 238 | Glu 238 | engineered mutation |
| Ala 239 | Glu 239 | engineered mutation |
| Ala 240 | Arg 240 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 85730.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 196.2 | |
| All* | Total formula weight | 85926.4 |
