5U8F
Polycomb protein EED in complex with inhibitor: (3R,4S)-1-[(1S)-7-fluoro-2,3-dihydro-1H-inden-1-yl]-N,N-dimethyl-4-(1-methyl-1H-indol-3-yl)pyrrolidin-3-amine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Polycomb protein EED | polymer | 369 | 42583.5 | 1 | UniProt (O75530) Pfam (PF00400) | Homo sapiens (Human) | hEED,WD protein associating with integrin cytoplasmic tails 1,WAIT-1 |
| 2 | B (A) | (3R,4S)-1-[(1S)-7-fluoro-2,3-dihydro-1H-inden-1-yl]-N,N-dimethyl-4-(1-methyl-1H-indol-3-yl)pyrrolidin-3-amine | non-polymer | 377.5 | 1 | Chemie (82G) | |||
| 3 | C (A) | water | water | 18.0 | 263 | Chemie (HOH) |
Sequence modifications
A: 77 - 441 (UniProt: O75530)
| PDB | External Database | Details |
|---|---|---|
| Gly 73 | - | expression tag |
| Ser 74 | - | expression tag |
| His 75 | - | expression tag |
| Met 76 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42583.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 377.5 | |
| All* | Total formula weight | 42961.0 |
