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5U46

Human PPARdelta ligand-binding domain in complexed with GW501516

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Peroxisome proliferator-activated receptor deltapolymer27231114.22UniProt (Q03181)
Pfam (PF00104)
Homo sapiens (Human)PPAR-delta,NUCI,Nuclear hormone receptor 1,NUC1,Nuclear receptor subfamily 1 group C member 2,Peroxisome proliferator-activated receptor beta,PPAR-beta
2C, H
(A)
heptyl beta-D-glucopyranosidenon-polymer278.32Chemie (B7G)
3D, F
(A)
S-1,2-PROPANEDIOLnon-polymer76.12Chemie (PGO)
4E, I
(A, B)
DI(HYDROXYETHYL)ETHERnon-polymer106.12Chemie (PEG)
5G, J
(A, B)
{2-methyl-4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]phenoxy}acetic acidnon-polymer453.52Chemie (7T1)
6K, L
(A, B)
waterwater18.0246Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight62228.4
Non-Polymers*Number of molecules8
Total formula weight1828.1
All*Total formula weight64056.5
*Water molecules are not included.

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PDB entries from 2025-12-24

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