5U2M

Crystal structure of human NAMPT with A-1293201

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Nicotinamide phosphoribosyltransferase	polymer	477	54120.4	2	UniProt (P43490) Pfam (PF18127) Pfam (PF04095)	Homo sapiens (Human)	Nampt,Pre-B-cell colony-enhancing factor 1,Pre-B cell-enhancing factor,Visfatin
2	C, G (A, B)	N-[4-({[(3S)-oxolan-3-yl]methyl}carbamoyl)phenyl]-1,3-dihydro-2H-isoindole-2-carboxamide	non-polymer		365.4	2	Chemie (7T7)
3	D, E, F, H, I... (A, B)	SULFATE ION	non-polymer		96.1	6	Chemie (SO4)
4	K, L (A, B)	water	water		18.0	623	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	108240.7
Non-Polymers*	Number of molecules	8
	Total formula weight	1307.2
All*	Total formula weight	109547.9

*Water molecules are not included.