5U1M
Structure of the IRS-1 PTB Domain Bound to the Juxtamembrane Region of the Insulin Receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Insulin receptor substrate 1 | polymer | 105 | 11832.8 | 1 | UniProt (P35568) Pfam (PF02174) | Homo sapiens (Human) | IRS-1 |
| 2 | B (B) | Insulin receptor | polymer | 10 | 1091.1 | 1 | UniProt (P06213) | Homo sapiens (Human) | IR |
| 3 | C, D (A, B) | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
A: 161 - 265 (UniProt: P35568)
B: 1001 - 1009 (UniProt: P06213)
| PDB | External Database | Details |
|---|---|---|
| Ala 263 | Glu 263 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ace 1000 | - | acetylation |
| Ala 1008 | Glu 998 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 12923.8 | |
| All* | Total formula weight | 12923.8 |
