5U1L
Crystal structure of the ATP-gated P2X7 ion channel in the closed, apo state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | P2X purinoceptor | polymer | 342 | 38716.2 | 1 | UniProt (G1M6C4) Pfam (PF00864) | Ailuropoda melanoleuca (Giant panda) | |
| 2 | B, C (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence modifications
A: 23 - 358 (UniProt: G1M6C4)
| PDB | External Database | Details |
|---|---|---|
| Gly 21 | - | expression tag |
| Ser 22 | - | expression tag |
| Ala 35 | Val 36 | engineered mutation |
| Ala 125 | Arg 126 | engineered mutation |
| Lys 174 | Glu 175 | engineered mutation |
| Ser 241 | Asn 242 | engineered mutation |
| Ser 284 | Asn 285 | engineered mutation |
| Ser 359 | - | expression tag |
| Ala 360 | - | expression tag |
| Ser 361 | - | expression tag |
| Ser 362 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38716.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 39158.6 |
