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5TYW

DNA Polymerase Mu Reactant Complex, Mn2+ (10 min)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA-directed DNA/RNA polymerase mupolymer35640054.41UniProt (Q9NP87)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (Human)Pol Mu,Terminal transferase
2B
(T)
DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3')polymer92740.81unidentified
3C
(P)
DNA (5'-D(*CP*GP*TP*AP*T)-3')polymer51495.01unidentified
4D
(D)
DNA (5'-D(P*GP*CP*CP*G)-3')polymer41191.81unidentified
5E
(A)
THYMIDINE-5'-TRIPHOSPHATEnon-polymer482.21Chemie (TTP)
6F
(A)
PYROPHOSPHATEnon-polymer178.01Chemie (PPV)
7G, H, I, J, Q...
(A, T, P)
MANGANESE (II) IONnon-polymer54.96Chemie (MN)
8K
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
9L
(A)
2,3-DIHYDROXY-1,4-DITHIOBUTANEnon-polymer154.31Chemie (DTT)
10M, N, O, S
(A, P)
1,2-ETHANEDIOLnon-polymer62.14Chemie (EDO)
11P
(A)
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.31Chemie (EPE)
12T, U, V, W
(A, T, P, D)
waterwater18.0377Chemie (HOH)
Sequence modifications
A: 132 - 494 (UniProt: Q9NP87)
PDBExternal DatabaseDetails
Gly 127-expression tag
Ser 128-expression tag
Ala 129-expression tag
Ala 130-expression tag
Ala 131-expression tag
-Pro 398deletion
-Gly 399deletion
-Ala 400deletion
-Ala 401deletion
-Val 402deletion
-Gly 403deletion
-Gly 404deletion
-Ser 405deletion
-Thr 406deletion
-Arg 407deletion
-Pro 408deletion
-Cys 409deletion
Gly 410Pro 410conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight45482.1
Non-Polymers*Number of molecules15
Total formula weight1653.6
All*Total formula weight47135.7
*Water molecules are not included.

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PDB entries from 2024-11-06

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