5TYT

Crystal Structure of the PDZ domain of RhoGEF bound to CXCR2 C-terminal peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Rho guanine nucleotide exchange factor 11, C-X-C chemokine receptor type 2 chimera	polymer	89	9355.9	4	UniProt (O15085) UniProt (P25025) Pfam (PF00595)	Homo sapiens (Human)	PDZ-RhoGEF,CXCR-2, CDw128b, GRO/MGSA receptor, High affinity interleukin-8 receptor B, IL-8R B, IL-8 receptor type 2
2	E, F, G, H (A, B, C, D)	water	water		18.0	13	Chemie (HOH)

Sequence modifications

A, B, C, D: 41 - 123 (UniProt: O15085)

PDB	External Database	Details
Met 40	-	cloning artifact

A, B, C, D: 124 - 128 (UniProt: P25025)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	37423.7
All*	Total formula weight	37423.7

*Water molecules are not included.