5TX3
Structure of Maternal Embryonic Leucine Zipper Kinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Maternal embryonic leucine zipper kinase | polymer | 344 | 39657.0 | 2 | UniProt (Q14680) Pfam (PF00069) Pfam (PF21594) | Homo sapiens (Human) | hMELK,Protein kinase Eg3,pEg3 kinase,Protein kinase PK38,hPK38,Tyrosine-protein kinase MELK |
| 2 | C, D (A, B) | 7-[(1S)-4-hydroxy-2,3-dihydro-1H-inden-1-yl]-5,5-dimethyl-2-({3-[(pyrrolidin-1-yl)methyl]phenyl}amino)-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one | non-polymer | 469.6 | 2 | Chemie (7MY) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 340 (UniProt: Q14680)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79313.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 939.2 | |
| All* | Total formula weight | 80253.1 |
