5TW6
CTX-M-14 P167S:E166A mutant with acylated ceftazidime molecule
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase | polymer | 263 | 27932.5 | 1 | UniProt (Q9L5C7) Pfam (PF00144) Pfam (PF13354) | Escherichia coli | |
| 2 | B (A) | ACYLATED CEFTAZIDIME | non-polymer | 469.5 | 1 | Chemie (CAZ) | |||
| 3 | C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | E (A) | water | water | 18.0 | 248 | Chemie (HOH) |
Sequence modifications
A: 25 - 290 (UniProt: Q9L5C7)
| PDB | External Database | Details |
|---|---|---|
| Ala 166 | Glu 169 | engineered mutation |
| Ser 167 | Pro 170 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27932.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 593.6 | |
| All* | Total formula weight | 28526.1 |
