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5TUV

Crystal structure of the E2F5-DP1-p107 ternary complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D
(A, D)
Transcription factor DP1polymer15517603.12UniProt (Q14186)
Pfam (PF08781)
Homo sapiens (Human)DRTF1-polypeptide 1,DRTF1,E2F dimerization partner 1
2B, E
(B, E)
Transcription factor E2F5polymer11212962.72UniProt (Q15329)
Pfam (PF16421)
Homo sapiens (Human)E2F-5
3C, F
(C, F)
Retinoblastoma-like protein 1polymer414663.32UniProt (P28749)
Pfam (PF08934)
Homo sapiens (Human)107 kDa retinoblastoma-associated protein,p107,pRb1
Sequence modifications
A, D: 199 - 350 (UniProt: Q14186)
PDBExternal DatabaseDetails
Gly 196-expression tag
Glu 197-expression tag
Phe 198-expression tag
B, E: 124 - 232 (UniProt: Q15329)
PDBExternal DatabaseDetails
Gly 121-expression tag
His 122-expression tag
Met 123-expression tag
C, F: 994 - 1031 (UniProt: P28749)
PDBExternal DatabaseDetails
Gly 991-expression tag
Glu 992-expression tag
Phe 993-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight70458.4
All*Total formula weight70458.4
*Water molecules are not included.

226707

PDB entries from 2024-10-30

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