5TTG
Crystal structure of catalytic domain of GLP with MS012
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Histone-lysine N-methyltransferase EHMT1 | polymer | 287 | 32974.3 | 2 | UniProt (Q9H9B1) Pfam (PF05033) Pfam (PF00856) In PDB | Homo sapiens (Human) | Euchromatic histone-lysine N-methyltransferase 1,Eu-HMTase1,G9a-like protein 1,GLP1,Histone H3-K9 methyltransferase 5,H3-K9-HMTase 5,Lysine N-methyltransferase 1D |
2 | A, B | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) | |||
3 | A, B | N4-(1-methylpiperidin-4-yl)-N2-hexyl-6,7-dimethoxyquinazoline-2,4-diamine | non-polymer | 401.5 | 2 | Chemie (7KZ) | |||
4 | A, B | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
5 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
6 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
7 | B, A | UNKNOWN ATOM OR ION | non-polymer | 15 | Chemie (UNX) | ||||
8 | B | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
9 | water | water | 18.0 | 633 | Chemie (HOH) |
Sequence modifications
A, B: 982 - 1266 (UniProt: Q9H9B1)
PDB | External Database | Details |
---|---|---|
Gly 980 | - | expression tag |
Ser 981 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 65948.7 | |
Non-Polymers* | Number of molecules | 30 |
Total formula weight | 2328.9 | |
All* | Total formula weight | 68277.6 |