5TS1
Crystal structure of MHC-I H2-KD complexed with peptides of Mycobacterial tuberculosis (YYQSGLSIV)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J (A, C, E, G) | H-2 class I histocompatibility antigen, K-D alpha chain | polymer | 275 | 32164.8 | 4 | UniProt (P01902) Pfam (PF00129) Pfam (PF07654) | Mus musculus (Mouse) | H-2K(D) |
| 2 | B, E, H, K (B, D, F, H) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 4 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C, F, I, L (P, Q, R, S) | Peptide (P9) of Mtb85B (Mycobacterium tuberculosis) YYQSGLSIV | polymer | 9 | 1029.1 | 4 | UniProt (P9WQP1) | Mycobacterium tuberculosis | DGAT,30 kDa extracellular protein,Acyl-CoA:diacylglycerol acyltransferase,Antigen 85 complex B,Ag85B,Extracellular alpha-antigen,Fibronectin-binding protein B,Fbps B |
| 4 | M, N, R, S, T... (A, D, F, G, H) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 5 | O, P, Q (A, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 6 | AA, BA, CA, DA, EA... (Q, E, F, R, G...) | water | water | 18.0 | 472 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 2 - 276 (UniProt: P01902)
B, D, F, H: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| His 114 | Gln 135 | conflict |
| Pro 276 | Leu 297 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 180293.1 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 738.8 | |
| All* | Total formula weight | 181031.9 |
