5TRZ
Crystal structure of MHC-I H2-KD complexed with peptides of Mycobacterial tuberculosis (YQSGLSIVM)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, C) | H-2 class I histocompatibility antigen, K-D alpha chain | polymer | 275 | 32164.8 | 2 | UniProt (P01902) Pfam (PF00129) Pfam (PF07654) | Mus musculus (Mouse) | H-2K(D) |
| 2 | B, E (B, D) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C, F (P, Q) | Peptide (P9) of Mtb85B (Mycobacterium tuberculosis) YQSGLSIVM | polymer | 9 | 997.2 | 2 | UniProt (P9WQP1) | Mycobacterium tuberculosis | DGAT,30 kDa extracellular protein,Acyl-CoA:diacylglycerol acyltransferase,Antigen 85 complex B,Ag85B,Extracellular alpha-antigen,Fibronectin-binding protein B,Fbps B |
| 4 | G, J, K (A, B, C) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | H, I, L, M, N... (A, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 6 | R, S, T, U, V... (A, B, P, C, D...) | water | water | 18.0 | 276 | Chemie (HOH) |
Sequence modifications
A, C: 2 - 276 (UniProt: P01902)
B, D: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| His 114 | Gln 135 | conflict |
| Pro 276 | Leu 297 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 90082.6 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 772.8 | |
| All* | Total formula weight | 90855.4 |
