5TR2

Crystal structure of the D263G missense variant of human PGM1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Phosphoglucomutase-1	polymer	585	64213.7	2	UniProt (P36871) Pfam (PF02878) Pfam (PF02879) Pfam (PF02880)	Homo sapiens (Human)	PGM 1,Glucose phosphomutase 1
2	C, D, E, H (A, B)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
3	F, I (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4	G (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5	J, K (A, B)	water	water		18.0	204	Chemie (HOH)

Sequence modifications

A, B: 1 - 562 (UniProt: P36871)

PDB	External Database	Details
Met -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
Ser -15	-	expression tag
Ser -14	-	expression tag
Gly -13	-	expression tag
Val -12	-	expression tag
Asp -11	-	expression tag
Leu -10	-	expression tag
Gly -9	-	expression tag
Thr -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Ser -1	-	expression tag
Asn 0	-	expression tag
Gly 263	Asp 263	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	128427.4
Non-Polymers*	Number of molecules	7
	Total formula weight	556.5
All*	Total formula weight	128983.9

*Water molecules are not included.