5TR1
Cryo-electron microscopy structure of a bovine CLC-K chloride channel, alternate (class 2) conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, B) | Chloride channel protein | polymer | 671 | 73521.5 | 2 | UniProt (E1B792) Pfam (PF00654) | Bos taurus (Bovine) | |
| 2 | B, E (H, I) | Monoclonal antibody, Fab fragment, heavy chain | polymer | 113 | 12633.1 | 2 | Mus musculus (house mouse) | ||
| 3 | C, F (L, M) | Monoclonal antibody, Fab fragment, light chain | polymer | 107 | 11824.1 | 2 | Mus musculus (house mouse) | ||
| 4 | G, H (A, B) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 2 | Chemie (Y01) PubChem (16219150) PubChem (22210610) PubChem (65082) PubChem (363416) PubChem (45489984) PubChem (500055) PubChem (60078761) PubChem (57163942) PubChem (73440805) PubChem (89891013) PubChem (13301926) PubChem (13301927) PubChem (99567469) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (11969853) PubChem (124301053) PubChem (124302591) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (137392566) PubChem (137496323) PubChem (124914595) PubChem (124914596) PubChem (131705526) PubChem (155804219) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (169132514) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028) |
Sequence modifications
A, B: 27 - 687 (UniProt: E1B792)
| PDB | External Database | Details |
|---|---|---|
| Met 26 | - | initiating methionine |
| Gln 373 | Asn 373 | engineered mutation |
| Ser 688 | - | expression tag |
| Asn 689 | - | expression tag |
| Ser 690 | - | expression tag |
| Leu 691 | - | expression tag |
| Glu 692 | - | expression tag |
| Val 693 | - | expression tag |
| Leu 694 | - | expression tag |
| Phe 695 | - | expression tag |
| Gln 696 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 195957.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 973.5 | |
| All* | Total formula weight | 196930.8 |
