5TR1
Cryo-electron microscopy structure of a bovine CLC-K chloride channel, alternate (class 2) conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, B) | Chloride channel protein | polymer | 671 | 73521.5 | 2 | UniProt (E1B792) Pfam (PF00654) | Bos taurus (Bovine) | |
| 2 | B, E (H, I) | Monoclonal antibody, Fab fragment, heavy chain | polymer | 113 | 12633.1 | 2 | Mus musculus (house mouse) | ||
| 3 | C, F (L, M) | Monoclonal antibody, Fab fragment, light chain | polymer | 107 | 11824.1 | 2 | Mus musculus (house mouse) | ||
| 4 | G, H (A, B) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 2 | Chemie (Y01) |
Sequence modifications
A, B: 27 - 687 (UniProt: E1B792)
| PDB | External Database | Details |
|---|---|---|
| Met 26 | - | initiating methionine |
| Gln 373 | Asn 373 | engineered mutation |
| Ser 688 | - | expression tag |
| Asn 689 | - | expression tag |
| Ser 690 | - | expression tag |
| Leu 691 | - | expression tag |
| Glu 692 | - | expression tag |
| Val 693 | - | expression tag |
| Leu 694 | - | expression tag |
| Phe 695 | - | expression tag |
| Gln 696 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 195957.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 973.5 | |
| All* | Total formula weight | 196930.8 |
