5TPZ
Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2B in apo closed state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NMDA glutamate receptor subunit | polymer | 383 | 42932.1 | 1 | UniProt (Q91977) Pfam (PF01094) UniProt (by SIFTS) (A0A1L8F5J9) | Xenopus laevis (African clawed frog) | |
| 2 | B (D) | Glutamate receptor ionotropic, NMDA 2B | polymer | 362 | 41149.6 | 1 | UniProt (Q00960) Pfam (PF01094) | Rattus norvegicus (Rat) | GluN2B,Glutamate [NMDA] receptor subunit epsilon-2,N-methyl D-aspartate receptor subtype 2B,NR2B |
| 3 | C, D, E, F (A, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 4 | G, H (A, D) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A: 23 - 405 (UniProt: Q91977)
D: 32 - 393 (UniProt: Q00960)
| PDB | External Database | Details |
|---|---|---|
| Gln 61 | Asn 61 | engineered mutation |
| Gln 371 | Asn 371 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Asp 348 | Asn 348 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 84081.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 84966.5 |
